Clip DSB assay with quantiles per feature — ClipDSB • pochi

Clip DSB assay with quantiles per feature

Usage

ClipDSB(
  object,
  assay = "DSB",
  slot = "data",
  split.by = NULL,
  low.p = NULL,
  high.p = 0.999,
  new.assay = "sDSB"
)

Arguments

object: Seurat object
assay: Which assay, typically DSB
slot: Which slot in the assay, typically data after DSB correction
split.by: If not NULL, which metadata feature to split by before scaling.
low.p: Which percentile below which to clip per feature
high.p: Which percentile above which to clip per feature
new.assay: Name of new assay to save values to

Value

Returns a Seurat object with clipped values in the data slot of the specified assay

Details

Clips the expression values for each feature in the specified assay from low.p to high.p, with an optional split.by argument.